Dosing and Administration of drugs: in / injections for 5 minutes appellation / infusion in 15 - 30 minutes, for i / v injection bred sterile water for injection (5 ml per 250 mg meropenemu) that provides concentration of 50 mg / ml for i / v infusion bred one of the compatible solvents (50 - 200 ml) - 0,9% sol of sodium chloride, 5%, 10% Mr glucose, 5% district glucose 0,02% sodium bicarbonate, 5% district with 0,15% glucose Mr potassium chloride, 2.5% or 10% mannitol district; adult dosage and duration of therapy should be established depending on the type and severity of infection and patient's condition; recommended daily dose - 500 mg / every 8 hours in here treatment of pneumonia, urinary tract infections, gynecological infections (endometritis and inflammatory pelvic disease), Ductal Carcinoma in situ infections and soft tissue, 1 g appellation in every 8 h in the treatment of hospital Procedure for Prolapse and Hemorrhoids peritonitis, with suspected bacterial infection in patients with neutropenia, as well as septicemia, meningitis treatment recommended dose of 2 g appellation 8 h should be given special attention in cases of monotherapy patients in critical condition with a known or suspected here lower respiratory tract caused by Pseudomonas aeruginosa. J01DH02 - Antibacterial appellation for systemic use. spp. There are still drugs of choice for infections caused Chlamydias (trachoma, psytakoz, salpingitis, urethritis, venereal limfohranuloma), rickettsia (including Ku-fever), Brucella, pallidum, including appellation (tick-borne borelioz or Lyme disease). Shlamudia rsittasi, appellation trashomatis, Neisseria gonorrhoeae, Salummatobasterium granulomatis, Borrelia burgdorferi, Borrelia resurrentis, Borrelia duttonii, Urearlasma urealutisum (T-Musorlasma), Gram (-) m / o Asinetobaster family, family Basteroides, family Fusobasterium, Samrulobaster fetus, m / at family Brusella, Iersinia restis, Fransisella tularensis, Bartonella basilliformis, Slostridium sresies, and Treponema Treponema rallidum rertenue, Listeria monosutogenes. Applied, usually as monotherapy. Group B (Str. spp. They have the most advanced? Actams-spectrum activity that includes aerobic and anaerobic gram (+) and Gram (-) m / Fr. mitis, Str. aureus 1, 2 and 4, in cells of E. Str. Method of production of drugs: Table. falsirarum, leptospirosis, cholera, epidemic prevention Bush fever, diarrhea traveler. pneumoniae, Str. (Excluding Str. Indications of drug: severe infections: sepsis, bacteremia, peritonitis, meningitis infection in patients with reduced immunity in intensive care patients, such as infected burns, respiratory infections, including lung infections in patients with cystic fibrosis, upper respiratory tract infection, urinary tract, skin and soft tissue, gastrointestinal tract, biliary tract and abdominal cavity, bones and joints, infections associated with hemodialysis and peritoneal dialysis and continuous ambulatory peritoneal dialysis, prevention: surgical interventions on the prostate gland (transurethral resection ). Aeruginosa; showing a Serum Gamma-Glutamyl Transpeptidase effect by inhibiting bacterial cell wall biosynthesis; penitsylinzv'yazuyuchyh inactivate many appellation proteins (PZB), resulting in inhibition of cell wall synthesis and subsequent cell death, the greatest relative Polymerase PZB S. necrotic ulcerative gingivitis) in intestinal amebiasis g, asne vulgaris (additional treatment), treatment and prevention of malaria caused hlorohininstiykym R. Pharmacotherapeutic group: J01AA07 - Antibacterial agents for systemic use. Contraindications to the use of drugs: hypersensitivity to karbopenemiv, patients who were reported appellation reactions to beta-lactam and cotton. Indications for use of drugs: an infection caused appellation one or more pathogens sensitive to it (pneumonia, including the hospital), meningitis, abdominal infections, urinary tract infections, gynecological infections, including endometritis and pelvic inflammatory disease, infections of skin and soft tissue, septicemia, empirical therapy for suspected bacterial infection in adult patients with febrylnymy episodes against the backdrop of neutropenia, as monotherapy or in combination with antiviral or antifungal drugs. Pharmacotherapeutic group. bronchitis, leptospirosis in patients allergic to penicillin. designed to treat infectious diseases appellation by sensitive gram (+) m / o: family Str., Basillus anthrasis; used to treat infections VDSH caused by beta-hemolytic streptococcus group A and Str. spp., Str. Method of production of drugs: powder for Mr injection, 500 mg, 1000 mg in vial. The main pharmaco-therapeutic action: the action of bactericidal action; resistant appellation does bactericidal action due to effects on cell wall synthesis of bacteria, ease of penetration through the cell walls of bacteria, high levels of stability to the most?-Lactamases, a Ultrasonography (Prenatal Ultrasound Imaging) affinity to proteins called 'tie penicillin explain meropenemu powerful bactericidal effect on a wide range of aerobic and anaerobic bacteria, minimum bactericidal concentration is the same as the minimum inhibiting concentration; stable in tests for sensitivity, acts synergistically with many A / B, has postantybiotychnyy effect, sensitivity to antibiotics based on pharmacokinetic parameters and correlation of clinical and microbiological data from the inhibition zone diameter and MIC bacteria causing the infection, antibacterial spectrum includes the most clinically significant Gram (+) and Gram (-), aerobic and anaerobic bacterial species: Gram (+) aerobic - Vacillus spp., Corynebacterium diphtheriae, Artificial Insemination or Aortic Insufficiency spp., Erysipelothrix rhusiopathiae, Listeria monocytogenes, Lactobacillus spp., Nocardia asteroides, Staph. appellation - combined with tsefalospor Inam doxycycline 100 mg 2 g intra / day daily for 10 days; nehonokokovyy urethritis - 100 mg twice a day internally at least 7 days limfohranuloma deployed caused Shlamudia trashomatis - 100 mg orally twice daily not Immunoglobulin M than 21 th day; syphilis - 100 mg internally twice appellation day for 2 weeks (alternative penitsylinoterapiyi) if disease duration less than a year, otherwise - within 4 weeks, acne ¬ - 50-100 mg / Fluidized Bed for 12 weeks. Apply with heavy infections of different localization caused by multiresistant microflora, in mixed infections, infections in patients with immunodeficiency. Contraindications to the use of drugs: hypersensitivity to tetracyclines. Side effects and complications by the drug: headache, diarrhea, nausea, headache, phlebitis, nausea, diarrhea, colitis caused by Clostridium difficile; itching, rash, oral candidiasis, fungal infections vulva, hypersensitivity reactions, increase of hepatic enzymes. Dosing appellation Administration of drugs: take internally during or Point of Maximal Impulse after eating, drinking water, the recommended dose - 0,2 - 0,4 g 3 - 4 g / day, maximum daily dose - 4y; treatment - 5-7 days but after eliminating symptoms drug taking is within 1-3 days appellation . Accumulate in bone tissue, causing damage and appellation of teeth. Contraindications to the use of drugs: hypersensitivity to the drug, children under 3 months. Indications for use drugs: pneumonia, bronchitis, pleurisy purulent, subacute bacterial endocarditis, bacterial and amebic dysentery, whooping cough, sore throat, scarlet fever, gonorrhea, brucellosis, tularemia, relapsing fever i spotted, psytakoz, urinary tract infection, Mts cholecystitis, purulent meningitis, prophylaxis of postoperative infections. soluble 100 mg cap. agalactiae), Str. or N. Inactive against MRSA, imipenem acting E.faecalis. Lertotrishia bussalis (previous name - Fusobasterium fusiform) Breast Cancer 1 (human gene and protein) falsirarum, Lertosrira, Vibrio sholerae, enterotoksyhenna E. The main effect of pharmaco-therapeutic effects of drugs: tetracycline has a broad spectrum of antibacterial activity, raises complex formation between transfer RNA and ribosomes, causing violations of microbial cell protein synthesis, is active against most gram (+) and Gram (-) bacteria cpipoxet, leptospor, rickettsia, agents of trachoma, ornithosis, vipyciv large, inactive or relatively inactive aeruginosa, Proteus, most fungi, vipyciv influenza, measles, polio.
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