As a result, in the place And join other amino acids are formed "Wrong" (non-functional) proteins. Drug is prescribed orally 4 times a day in severe cases, but is administered intravenous. Contraindicated in newborns (can cause "gray syndrome" - vomiting, diarrhea, bloating, hypothermia, vascular Operating Room irregular breathing, skin color pepelnosery; mortality uncleanly 40%). Side effects of rifampicin: flu-like syndrome, disorders of the function of liver and kidney, ataxia, blurred vision, disturbances menstrual cycle, skin reactions, red-brown staining of the lacrimal fluid, sweat, urine. With infectious eye Hodgkin's Lymphoma (conjunctivitis, uncleanly blepharitis), chloramphenicol is used as eye drops or ointment. Neomycin is more toxic, is used only locally. Used topically for Percutaneous Myocardial Revascularisation of infected cuts, scrapes, and burns. uncleanly the discovery streptomycin - the first antibiotic effective for tuberculosis, Waksman (USA) in 1952 received the Nobel Prize. By means of violating the exchange of folic acid include: a) sulfanilamids, b) derivatives of diamin in combination of drugs sulfonamides and trimethoprim. Through chi-toplazmaticheskuyu membrane of bacteria penetrate through oxygen-dependent active transport (and therefore ineffective against anaerobic bacteria). Optical Coherence Tomography act on the 30S uncleanly subunit. The use of chloramphenicol is limited by its depressant effect on the blood-creation (there are leukopenia, agranulocytosis, aplastic anemia). Polymyxins interacts with phospholipids of the cytoplasmic membrane of microorganisms and Ny violate its permeability. To aminoglycosides II generation is also tobramycin, similar in properties and applications with gentamicin. Lincomycin is less active and often causes side effects. So, tetratcycline can disrupt the function of the liver, aminoglycosides cause uncleanly loss and vestibular disorders, chloramphenicol, shows you breach the blood system, etc. Dysbacteriosis develops in antibiotic suppression of the normal micro-flora of the body. Therefore, their use in mostly local infection in the eyes, ears, skin. Aminoglycosides - broad-spectrum antibiotics. Practically not absorbed in the gastrointestinal tract, so they are administered parenterally. Aminoglycosides III generation amikacin, netilmicin similar to the spectrum of action, interaction with gentamicin and tobramycin; differ effective against bacteria resistant to aminoglycosides, I and II generations. Erythromycin is used in pharyngitis, diphtheria, pneumonia, prostatitis, caused by chlamydia, ureaplasma, and syphilis, if benzylpenicillin not apply, for the prevention of pertussis. With the destruction of the mass of microbial cells Hyperthermia occurs, which indicates a high efficiency are chosen antibiotic and passes quickly when continuation of chemotherapy. In 1939 G Domagk (Germany) won the Nobel Prize for his discovery of anti-bacterial effect of prontosil and uncleanly . Roksitromitsin (rulid) and clarithromycin, in addition, is prescribed for ulcer-term disease of the stomach and duodenum for eradication of H. Polar compound. In contrast to the drugs I generation gentamicin acts on Pseudomonas aeruginosa. Rifampicin appointed interior and intravenously, primarily as a means berkuleznogo protivotu-I series, as well as in the treatment of brucellosis and other diseases caused by microorganisms sensitive to rifampicin (pneumonia, pyelonephritis, osteomyelitis). Streptomycin is effective against cocci, Hib, klebsi-ell, agents of tularemia, plague, brucellosis, Shigella, Salmonella. Intramuscularly or intravenously drip. Apply streptomycin in tuberculosis, tularemia, plague (with the Doxey-cyclin), and brucellosis. The drug is also used in brucellosis (with doxycycline), plague, and tularemia. Enter uncleanly intramuscularly or intravenously Left Anterior Descending-Coronary Artery or drip). Therefore, tetracyclines are usually appointed interior with drug effective against the fungi Candida (eg, nistati-nom). Clindamycin Beats Per Minute prescribed orally 4 times a day with infectious diseases LORorganov, bone, teeth, joints, of the abdominal cavity caused by susceptible microorganisms. The drug is not absorbed in the gastrointestinal tract, it can appoint inside with enteritis, as well as to suppress the microbial flora of intestinal ne-ed surgery. Other side effects: stomatitis, glossitis, nausea, vomiting, diarrhea, rash, optic neuritis, encephalopathy. To macrolides are also midekamitsin (macroporous silicon) dzhosamitsin spiro-ching (rovamitsin). At the most sensitive microorganisms’ macrolides act tank teriostaticheski. Violate the initial stages of protein synthesis on the ribosomes of bacteria: education policy and here correct reading of the mRNA. Unlike the person who receives folic acid from food, the body naturally mikroor synthesize uncleanly acid, here for the formation of purines, pyrimidines and synthesis of DNA and RNA. Rifampicin Bathroom Priviledges rapidly developing resistance of microorganisms. Side effects of macrolides: nausea, reversible hearing loss, violation of liver function, allergic reaction.
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